食用添加剂网讯 2021年12月17日,据欧盟国家食品安全局(EFSA)信息,应欧洲委员会规定,欧盟国家小动物饲料添加物和商品(FEEDAP)科学研究团队就谷氨酸棒链球菌CGMCC 14498生产制造的L-赖氨酸盐酸盐和 L-磷酸氢钙硫氰酸钾(l‐lysine monohydrochloride and l‐lysine sulfate)做为所有动物饲料添加物的安全系数发布科学合理建议。
通过评定,权威专家工作组觉得该添加物对总体目标外来物种、顾客和条件全是安全性的。评定中的添加物被觉得是碳水化合物L-磷酸氢钙的合理来源于。为了更好地使填补的L-磷酸氢钙对食草动物和非反刍动物一样合理,必须控制其在瘤胃中溶解。一部分全文报导如下所示:
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l-lysine monohydrochloride (l-lysine HCl) and l-lysine sulfate produced by Corynebacterium glutamicum (C. glutamicum) CGMCC 14498 as a nutritional feed additive for all animal species. The active substance is l-lysine and it is produced in two different forms (monohydrochloride or sulfate). The production strain C. glutamicum CGMCC 14498 and its recombinant DNA were not detected in the final products. The products l-lysine HCl and l-lysine sulfate do not pose any safety concern associated with the production strain. l-Lysine HCl and l-lysine sulfate produced by C. glutamicum CGMCC 14498 are considered safe for the target species. When using l-lysine sulfate, the background sulfur/sulfate content in the compound feed should be taken into account. l-Lysine HCl and l-lysine sulfate produced by C. glutamicum CGMCC 14498 are safe for the consumer and the environment. In the absence of data, the FEEDAP Panel cannot conclude on the potential of l-lysine HCl produced by the strain C. glutamicum CGMCC 14498 to be toxic by inhalation, and on the potential of l-lysine HCl and l-lysine sulfate produced by the above-mentioned strain to be irritant to skin or eyes, or on their potential to be dermal sensitisers. l-Lysine HCl and l-lysine sulfate produced by C. glutamicum CGMCC 14498 are considered efficacious sources of the essential amino acid l-lysine for non-ruminant animal species. For the supplemental l-lysine to be as efficacious in ruminants as in non-ruminant species, this would require protection against degradation in the rumen.